Mohamed Bin Hammam on Monday announced that he had resigned from his roles on FIFA's executive committee and as president of the Asian Football Confederation.
The Qatari told AFP in an emailed statement that he had stepped down from the positions 10 days after the ethics committee of football's world governing body FIFA, launched a new probe into corruption claims against him.
FIFA responded to bin Hammam's statement by saying it had received his resignation letter but stressed its ethics committee remained competent to make and maintain a judgment "even if a person resigns".
The 63-year-old has been accused of trying to buy the result of a vote to the world governing body's top job in 2011 and was banned by FIFA from all footballing activities.
Last month, the AFC said it was looking to replace bin Hammam following a unanimous decision to hold presidential elections next year.
According to insiders, interim president Zhang Jilong of China is favourite to claim the post full-time.