Delicately poised at 1-1, it is the only one of the four ties level after the first leg and comes hard on the heels of Arsenal's FA Cup defeat by Manchester United on Saturday.

Tuesday's other game looks much more straightforward as Real Madrid take a 4-2 lead to Monaco in the fight to meet the winners of the London derby in the semi-finals.

Holders AC Milan also look likely to progress as they visit Deportivo Coruna with a 4-1 lead. Wednesday's other game sees Olympique Lyon trying to overturn a 2-0 deficit at home to Porto.

The forthcoming fixtures appeared to be on the minds of many of the teams involved at the weekend as only two of the eight quarter-finalists managed domestic victories.

Arsenal's hopes of a treble disappeared with their 1-0 FA Cup defeat to Manchester United on Saturday but manager Arsene Wenger would happily swap domestic success for an elusive taste of glory in Europe's premier competition.

The Frenchman's north London side, who have never gone beyond the last eight, have the advantage in terms of the away goal secured by Robert Pires in a tight, cagey first leg and Chelsea have to score to have any chance of progressing.

That has not proved a problem in the four games between the two teams this season but keeping goals out has -- Arsenal won the three previous domestic encounters 2-1.

However, Saturday's defeat to United, and the injuries to striker Jose Reyes and midfielder Freddie Ljungberg that came with it, have dented Arsenal's confidence.

Chelsea warmed up with their 12th premier league away win of the season, 1-0 at Tottenham Hotspur courtesy of a Jimmy Floyd Hasselbaink goal.

With clean sheets in an unblemished record of five wins on the road in Europe this season, leaving Stamford Bridge has not been a problem.

Highbury, however, remains an exception. Chelsea lost there in league and FA Cup this season and have not won a major game at the ground since 1990.

As if trying to turn round a 4-2 deficit against Real Madrid was not a tough enough prospect, Monaco will have to attempt it without several key players.

Midfield duo Lucas Bernardi (suspended) and Andreas Zikos are both out, as is outstanding centre back Sebastien Squillaci.

The French league leaders came from 3-0 down at halftime to draw 3-3 with AC Ajaccio on Friday and will need to show similar tenacity to have any chance of getting the minimum two goals required.

Real, who will be without suspended England midfielder David Beckham, beat Albacete 2-1 away on Saturday with two deflected Roberto Carlos free kicks.

Milan chose to rest Brazilian Kaka for most of Sunday's 1-1 draw at Modena but the on-song midfielder, who scored twice in first leg against Deportivo, should return to the starting lineup on Wednesday.

Andriy Shevchenko, who missed Sunday's game with a broken nose sustained playing for Ukraine last week, remains a doubt and Danish striker Jon Dahl Tomasson, who scored at Modena, is standing by to partner Filippo Inzaghi.

The Spaniards, who led in the San Siro before a 15-minute, four-goal blitz turned the tie around, drew 2-2 at home with Real Betis on Sunday.

Porto perhaps had an eye on Wednesday's trip to Lyon as they suffered their first league defeat of the season on Saturday, 2-0 at Gil Vicente.

Coach Jose Mourinho rested defender Nuno Valente and midfielder Costinha ahead of the European game.

Lyon also lost at the weekend, 2-1 at home to Olympique Marseille, and look certain to be without France striker Sidney Govou, who picked up an injury against Marseille.